Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 4/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19333109 | 0.89 | MEN1 (0.36) | KDM4EGAAALDH1A1ALOX15MAPK1 | |
| SCHEMBL8736028 | 0.83 | TP53 (0.52) | KDM4EGAATP53ALDH1A1ALOX15 | |
| SCHEMBL19333096 | 0.81 | SLC2A1 (0.37) | KDM4EGAATP53KMT2AMAPT | |
| SCHEMBL8737620 | 0.72 | TUBB4A (0.47) | GAATP53KMT2ALMNASMN1; SMN2 | |
| SCHEMBL19937876 | 0.70 | TP53 (0.46) | GAATP53ALDH1A1MAPK1KMT2A | |
| SCHEMBL8736025 | 0.64 | TP53 (0.52) | GAATP53ALDH1A1MAPK1KMT2A | |
| SCHEMBL8734880 | 0.64 | TP53 (0.52) | KDM4EGAATP53ALDH1A1KMT2A | |
| SCHEMBL8736001 | 0.63 | TP53 (0.56) | KDM4EGAATP53ALDH1A1MAPK1 | |
| SCHEMBL15308262 | 0.62 | CFTR (0.39) | TP53MAPK1POLBTNFNOD1 | |
| SCHEMBL25492192 | 0.60 | GAA (0.51) | GAATP53MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757381-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-09-12 | — | — | US | disclosed |