Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19333097 | 0.89 | KDM4E (0.43) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL8737620 | 0.84 | TUBB4A (0.47) | KMT2AGAAL3MBTL1TUBB4ATUBB | |
| SCHEMBL19937876 | 0.75 | TP53 (0.46) | KMT2AGAAMAPTL3MBTL1LMNA | |
| SCHEMBL8736028 | 0.72 | TP53 (0.52) | KMT2AKDM4EGAAL3MBTL1LMNA | |
| SCHEMBL19333096 | 0.70 | SLC2A1 (0.37) | KMT2AKDM4EGAAMAPTPOLB | |
| SCHEMBL25492200 | 0.70 | TUBB4A (0.48) | KMT2AKDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL11102824 | 0.67 | PDE4D (0.64) | MEN1KMT2AMAPTL3MBTL1TUBB4A | |
| SCHEMBL15308244 | 0.66 | TUBB4A (0.46) | KMT2AGAAMAPTL3MBTL1TUBB4A | |
| SCHEMBL25492191 | 0.66 | TUBB4A (0.51) | MEN1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL25492202 | 0.64 | TUBB4A (0.47) | KMT2AGAAL3MBTL1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757381-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-09-12 | — | — | US | disclosed |