Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19333369 | 1.00 | TSHR (0.43) | TSHRNISCHHTTKDM4EL3MBTL1 | |
| SCHEMBL19333357 | 0.88 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL19333373 | 0.88 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL17465964 | 0.83 | TRPA1 (0.41) | TSHR | |
| SCHEMBL7380015 | 0.81 | TRPA1 (0.31) | — | |
| SCHEMBL19879072 | 0.81 | — | — | |
| SCHEMBL24416891 | 0.78 | CHRM1 (0.30) | — | |
| SCHEMBL29557212 | 0.78 | CHRM1 (0.30) | — | |
| SCHEMBL29556957 | 0.77 | KDM4E (0.35) | KDM4E | |
| SCHEMBL24416886 | 0.77 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |