SCHEMBL19333357

SCHEMBL19333357

CCCC(C)c1ccccc1-c1nnn[nH]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19333373 1.00 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL19333369 0.88 TSHR (0.43) TSHR
SCHEMBL19333318 0.88 TSHR (0.43) TSHR
SCHEMBL29557212 0.84 CHRM1 (0.30)
SCHEMBL19879072 0.84
SCHEMBL24416891 0.84 CHRM1 (0.30)
SCHEMBL17465964 0.81 TRPA1 (0.41) ALDH1A1TSHR
SCHEMBL29556957 0.80 KDM4E (0.35) ALDH1A1
SCHEMBL24416886 0.80 KDM4E (0.35) ALDH1A1
SCHEMBL24416890 0.79 PPARG (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9895330-B2 IDO inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2018-02-20 US disclosed
US-9758492-B2 IDO inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-12 US disclosed