Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.44 |
| ▸ | ADH1C | P00326 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289972 | 0.90 | HTR1D (0.43) | HTR1DHTR1BDRD3DRD2DRD4 | |
| SCHEMBL2481382 | 0.85 | ADH1C (0.40) | ADH1AADH1CSLC6A2SLC6A4ADH1B | |
| SCHEMBL27826964 | 0.85 | ADH1A (0.42) | ADH1AADH1CHTR1DHTR1BDRD3 | |
| SCHEMBL19143811 | 0.83 | ADH1A (0.41) | ADH1AADH1CSLC6A2SLC6A4ADH1B | |
| SCHEMBL22541111 | 0.83 | ADH1A (0.54) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL11073680 | 0.83 | ADH1A (0.54) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL516269 | 0.83 | ADH1A (0.54) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL24272678 | 0.82 | SLC6A2 (0.36) | ADH1AADH1CSLC6A2SLC6A4ADH1B | |
| SCHEMBL20803994 | 0.82 | ADH1A (0.40) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL24437747 | 0.82 | DRD3 (0.41) | ADH1AADH1CDRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |