SCHEMBL2481382

SCHEMBL2481382

CC(C)CN(CC(C)C)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADH1C P00326 3/20 0.40
ADH1A P07327 3/20 0.40
ADH1B P00325 1/20 0.40
SLC6A2 P23975 11/20 0.40
SLC6A4 P31645 10/20 0.40
PIK3CD O00329 1/20 0.39
SLC6A3 Q01959 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26767657 0.95 SLC6A2 (0.42) SLC6A2SLC6A4PIK3CDSLC6A3
SCHEMBL19143811 0.89 ADH1A (0.41) ADH1CADH1AADH1BSLC6A2SLC6A4
SCHEMBL23733657 0.87 SLC6A2 (0.43) SLC6A2SLC6A4PIK3CDSLC6A3
SCHEMBL9288887 0.86 SLC6A2 (0.38) ADH1CADH1AADH1BSLC6A2SLC6A4
SCHEMBL19333335 0.85 ADH1A (0.44) ADH1CADH1AADH1BSLC6A2SLC6A4
SCHEMBL24272678 0.83 SLC6A2 (0.36) ADH1CADH1AADH1BSLC6A2SLC6A4
SCHEMBL20780304 0.83 SLC6A2 (0.39) ADH1CADH1ASLC6A2SLC6A4PIK3CD
SCHEMBL810839 0.81 ADH1C (0.38) ADH1CADH1AADH1B
SCHEMBL25142287 0.81 ADH1A (0.38) ADH1CADH1AADH1BPIK3CD
SCHEMBL11626207 0.81 ADH1C (0.38) ADH1CADH1AADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503946-B The manufacturing method of hydroxymethyl phosphonic acid ester, polyurethane foam formation composition, polyurethane foam and the product being made from it ICL-IP美国公司 2018-10-12 CN claimed
CN-105503946-A Method for making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP America Inc 2016-04-20 CN claimed
CN-102256987-B Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL-IP AMERICA INC. (US) 2016-01-13 CN claimed
US-9187504-B2 Method of making hydroxymethylphosphonate ICL-IP AMERICA INC. (US) 2015-11-17 US claimed
EP-2376507-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATES ICL IP AMERICA INC (US) 2013-05-15 EP claimed
US-8198341-B2 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. (US) 2012-06-12 US claimed
CN-102256987-A Hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foams, and methods of making articles made therefrom ICL IP AMERICAN CORP 2011-11-23 CN claimed
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom STOWELL JEFFREY K 2011-10-20 US claimed
EP-2376507-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM ICL-IP America Inc. (US) 2011-10-19 EP claimed
WO-2010080425-A1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS POLYURETHANE FOAM AND ARTICLES MADE THEREFORM SUPRESTA LLC. (US) 2010-07-15 WO claimed
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom ICL-IP AMERICA INC. 2010-06-24 US claimed
CN-107383093-B Hydroxymethylphosphonate, compositions, polyurethane foams, and articles ICL-IP美国有限公司 2021-07-16 CN disclosed
EP-3553068-B1 YDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL IP AMERICA INC (US) 2021-04-28 EP disclosed
EP-3553068-A1 HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP America Inc. (US) 2019-10-16 EP disclosed
EP-2909218-B1 METHOD OF MAKING HYDROXYMETHYLPHOSPHONATE, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL IP AMERICA INC (US) 2019-07-10 EP disclosed
US-5420356-A Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-30 US disclosed
EP-0638537-A1 Process for producing cyclobutanones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-15 EP disclosed
EP-0382053-B1 PROCESS FOR THE PREPARATION OF ANTHRAQUINONE DERIVATIVES BASF Aktiengesellschaft (DE) 1993-09-22 EP disclosed
EP-0382053-A2 Process for the preparation of anthraquinone derivatives BASF Aktiengesellschaft (DE) 1990-08-16 EP disclosed
US-4137261-A Manufacture of N-vinyl-N-alkyl-carbamic acid chlorides BASF AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110257287-A1 Method of Making Hydroxymethylphosphonate, Polyurethane Foam-Forming Compositions, Polyurethane Foam and Articles Made Therefrom PFAS, PGM2, NEFM ADH1C 1581/4885ADH1A 1854/4885ADH1B 3071/4885
US-20100160468-A1 Method of making hydroxymethylphosphonate, polyurethane foam-forming compositions, polyurethane foam and articles made therefrom PFAS, PGM2, NEFM ADH1C 1581/4885ADH1A 1854/4885ADH1B 3071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.