Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 10/20 | 0.36 |
| ▸ | ACE | P12821 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531994 | 1.00 | MCL1 (0.44) | MCL1MAPK1SRD5A2MMEACE | |
| SCHEMBL993051 | 0.98 | MCL1 (0.45) | MCL1MAPK1SRD5A2MMEACE | |
| SCHEMBL8028222 | 0.93 | MCL1 (0.39) | MCL1MAPK1SRD5A2SMN1; SMN2GAA | |
| SCHEMBL6225198 | 0.91 | MGLL (0.40) | MCL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL38409 | 0.90 | MCL1 (0.57) | MCL1MMEACESMN1; SMN2GAA | |
| SCHEMBL8014971 | 0.90 | MCL1 (0.57) | MCL1MMEACESMN1; SMN2GAA | |
| SCHEMBL8645790 | 0.89 | MCL1 (0.55) | MCL1MMEACESMN1; SMN2MEN1 | |
| SCHEMBL8935361 | 0.88 | CA1 (0.40) | MCL1MAPK1MMEACESMN1; SMN2 | |
| SCHEMBL7721046 | 0.88 | ABL1 (0.38) | MCL1MAPK1MMEACESMN1; SMN2 | |
| SCHEMBL9621799 | 0.87 | MCL1 (0.43) | MCL1MMEACESMN1; SMN2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461422-A2 | Thermoplastic moulding compositions containing polyphenylene ester and a polyester | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-12-18 | — | — | EP | claimed |
| WO-2011066616-A1 | POLYMERIC MATERIALS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-06-09 | — | — | WO | disclosed |
| WO-2009065765-A2 | POLYAMIDE COMPOSITIONS FOR POLYAMIDE-BASED CORDS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-05-28 | — | — | WO | disclosed |
| EP-0461422-A2 | Thermoplastic moulding compositions containing polyphenylene ester and a polyester | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0436802-A2 | Capped polyphenylenether | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | disclosed |