Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993051 | 0.95 | MCL1 (0.45) | MCL1ABL1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL10531994 | 0.93 | MCL1 (0.44) | MCL1ABL1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL1933595 | 0.93 | MCL1 (0.44) | MCL1ABL1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL38246 | 0.91 | MCL1 (0.50) | MCL1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11037176 | 0.89 | SMN1; SMN2 (0.44) | MCL1MAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8645790 | 0.89 | MCL1 (0.55) | MCL1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL6225198 | 0.87 | MGLL (0.40) | MCL1MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8436391 | 0.87 | CES1 (0.44) | MAPK1MEN1KMT2ASRD5A2GAA | |
| SCHEMBL8014971 | 0.86 | MCL1 (0.57) | MCL1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL38409 | 0.86 | MCL1 (0.57) | MCL1HDAC3HDAC11HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826025-B1 | USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS | BASF AG (DE) | 2000-03-01 | — | — | EP | claimed |
| EP-0756622-B1 | BLEACH COMPOSITIONS COMPRISING PROTEASE ENZYME | PROCTER & GAMBLE (US) | 1999-12-15 | — | — | EP | claimed |
| EP-0754219-B1 | BLEACH COMPOSITIONS COMPRISING BLEACH ACTIVATORS AND BLEACH CATALYSTS | PROCTER & GAMBLE (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0826025-B1 | USE OF HETEROCYCLIC COMPOUNDS AS ACTIVATORS FOR INORGANIC PEROXY COMPOUNDS | BASF AG (DE) | 2000-03-01 | — | — | EP | disclosed |