SCHEMBL1933672

SCHEMBL1933672

CCCCCCCCCCCCCC(=O)OCC(C)(C)C=O.CCCCCCCCCCCCCCCC(=O)OCC(C)(C)C=O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGKA P23743 2/20 0.56
TSHR P16473 1/20 0.53
PAM P19021 2/20 0.51
MAPT P10636 1/20 0.49
LMNA P02545 4/20 0.47
DNM1 Q05193 1/20 0.47
ALDH1A1 P00352 1/20 0.47
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
PRKCA P17252 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9935881 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL340251 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL197167 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL342390 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL3110064 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL341269 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL9935331 1.00 DGKA (0.56) DGKATSHRPAMMAPTLMNA
SCHEMBL2845569 0.98 DGKA (0.53) DGKATSHRPAMMAPTLMNA
SCHEMBL2847460 0.93 DGKA (0.46) DGKATSHRPAMMAPTLMNA
SCHEMBL4425044 0.93 DGKA (0.44) DGKATSHRPAMMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673089-B2 Aldimine cleaning composition for reactive polyurethane compositions SIKA TECHNOLOGY AG (CH) 2014-03-18 US disclosed
EP-2507279-A2 ALDIMINE CLEANING COMPOSITION FOR REACTIVE POLYURETHANE COMPOSITIONS Sika Technology AG (CH) 2012-10-10 EP disclosed
US-20120245069-A1 ALDIMINE CLEANING COMPOSITION FOR REACTIVE POLYURETHANE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2012-09-27 US disclosed
US-8178167-B2 VOC-free or VOC-poor polyurethane coating SIKA TECHNOLOGY AG (CH) 2012-05-15 US disclosed
WO-2011067168-A2 ALDIMINE CLEANING COMPOSITION FOR REACTIVE POLYURETHANE COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-06-09 WO disclosed
EP-2330140-A1 Cleaning composition for reactive polyurethane compositions based on aldimines Sika Technology AG (CH) 2011-06-08 EP disclosed
EP-2145907-B1 Amorphous polyurethane polymer and use thereof in hotmelt adhesives SIKA TECHNOLOGY AG (CH) 2010-12-22 EP disclosed
EP-2038323-B1 VOC-FREE OR VOC-POOR POLYURETHANE COATING SIKA TECHNOLOGY AG (CH) 2010-08-18 EP disclosed
EP-2089447-B1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH SIKA TECHNOLOGY AG (CH) 2010-05-19 EP disclosed
EP-2145907-A1 Amorphous polyurethane polymer and use thereof in hotmelt adhesives Sika Technology AG (CH) 2010-01-20 EP disclosed
US-20100009076-A1 Voc-free or voc-poor polyurethane coating SIKA TECHNOLOGY AG (CH) 2010-01-14 US disclosed
EP-2089447-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH Sika Technology AG (CH) 2009-08-19 EP disclosed
EP-1923445-B1 Polyaldimine containing moisture curable hotmelt adhesive composition SIKA TECHNOLOGY AG (CH) 2009-06-24 EP disclosed
WO-2008059056-A1 MOISTURE-CURING HOT-MELT ADHESIVE COMPOUND CONTAINING POLYALDIMINE SIKA TECHNOLOGY AG (CH) 2008-05-22 WO disclosed
EP-1923445-A1 Polyaldimine containing moisture curable hotmelt adhesive composition Sika Technology AG (CH) 2008-05-21 EP disclosed
WO-2008052999-A1 POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH SIKA TECHNOLOGY AG (CH) 2008-05-08 WO disclosed
EP-1918314-A1 Polyurethane composition with high green strength Sika Technology AG (CH) 2008-05-07 EP disclosed
EP-1876196-A1 VOC free or low VOC polyurethane coating Sika Technology AG (CH) 2008-01-09 EP disclosed