Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845569 | 0.95 | DGKA (0.53) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL341269 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL1933672 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL342390 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL9935331 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL9935881 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL3110064 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL197167 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL340251 | 0.93 | DGKA (0.56) | DGKATSHRPAMMAPTLMNA | |
| SCHEMBL2846232 | 0.89 | ALDH1A1 (0.43) | DGKATSHRPAMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | claimed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | claimed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | claimed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465842-A1 | Amines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| US-20100130674-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | US | claimed |
| EP-2132246-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | claimed |
| WO-2008116927-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | claimed |
| EP-1975187-A1 | Method for manufacturing polyurethane compounds with low isocyanate-monomer content | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | claimed |
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| EP-2132248-B1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | disclosed |
| EP-2090601-B1 | Humidity reactive adhesive compositions with very low temperature dependency of shear modulus | SIKA TECHNOLOGY AG (CH) | 2016-02-17 | — | — | EP | disclosed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20090068479-A1 | Moisture-reactive adhesive compositions with very low temperature dependency of the shear modulus | SIKA TECHNOLOGY AG (CH) | 2009-03-12 | — | — | US | disclosed |
| WO-2008116927-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975187-A1 | Method for manufacturing polyurethane compounds with low isocyanate-monomer content | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | AAAS, PNMT, PARG | DGKA 3627/4885TSHR 4479/4885PAM 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.