Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | RGS4 | P49798 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RGS8 | P57771 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25867919 | 0.98 | RGS4 (0.43) | ADORA2BCNR2RGS4PTGS1PTGS2 | |
| SCHEMBL15984388 | 0.92 | RGS4 (0.35) | ADORA2BCNR2RGS4MGLLFAAH | |
| SCHEMBL19493726 | 0.89 | RGS4 (0.44) | CNR2RGS4TNFGSK3BRGS8 | |
| SCHEMBL20724125 | 0.86 | RGS4 (0.45) | ADORA2BCNR2RGS4GSK3BRGS8 | |
| SCHEMBL12787622 | 0.85 | MGLL (0.52) | ADORA2BCNR2RGS4PTGS1PTGS2 | |
| SCHEMBL11840543 | 0.85 | MGLL (0.52) | ADORA2BCNR2RGS4PTGS1PTGS2 | |
| SCHEMBL9626274 | 0.85 | MGLL (0.52) | ADORA2BCNR2RGS4PTGS1PTGS2 | |
| SCHEMBL4963710 | 0.85 | MGLL (0.52) | ADORA2BCNR2RGS4PTGS1PTGS2 | |
| SCHEMBL19493532 | 0.84 | RGS4 (0.37) | ADORA2BCNR2RGS4GSK3B | |
| SCHEMBL19700832 | 0.84 | CNR2 (0.34) | ADORA2BCNR2RGS4PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768877-B1 | POLYMERISABLE PLASTICISER, LIQUID POLYURETHANE RESIN COMPOSITION COMPRISING SAME AND USES THEREOF | SOPREMA (FR) | 2017-09-13 | — | — | EP | disclosed |
| EP-2768878-B1 | STABLE, READY-TO-USE LIQUID POLYURETHANE RESIN COMPOSITION AND USES THEREOF | SOPREMA (FR) | 2017-09-13 | — | — | EP | disclosed |