Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582840 | 0.73 | TMEM97 (0.53) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL3301756 | 0.71 | TMEM97 (0.51) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL6588314 | 0.70 | TMEM97 (0.50) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL4621924 | 0.70 | ALDH1A1 (0.59) | CYP1A2GAAMEN1KMT2ALMNA | |
| SCHEMBL6948825 | 0.67 | MEN1 (0.46) | TMEM97SIGMAR1HTR3AHTR4GAA | |
| SCHEMBL2777224 | 0.65 | TMEM97 (0.43) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL2777229 | 0.65 | TMEM97 (0.43) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL2777232 | 0.65 | TMEM97 (0.43) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL28357637 | 0.65 | MEN1 (0.51) | TMEM97SIGMAR1HTR3AHTR4CYP1A2 | |
| SCHEMBL5286253 | 0.64 | CYP1A2 (0.62) | CYP1A2GAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216786-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-09-13 | — | — | EP | disclosed |