SCHEMBL19337381

SCHEMBL19337381

COc1ccc(N)c2c1CCC2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 4/20 0.53
IDO1 P14902 1/20 0.44
EP300 Q09472 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42
ALDH1A1 P00352 7/20 0.42
CYP3A4 P08684 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
ADRA2B P18089 1/20 0.40
PTGS1 P23219 1/20 0.40
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16372577 0.96 ADRA1A (0.53) ADRA1AIDO1EP300KAT8ALDH1A1
SCHEMBL833885 0.87 ADRA1A (0.59) ADRA1AALDH1A1GAAKDM4EGLA
SCHEMBL10969055 0.82 ADRA1A (0.59) ADRA1AALDH1A1GAAKDM4EGLA
SCHEMBL4822580 0.79 ACHE (0.36) ALDH1A1CYP3A4TDP1TSHRGAA
SCHEMBL31511949 0.78 ADRA1A (0.48) ADRA1AIDO1EP300KAT8ALDH1A1
SCHEMBL2722920 0.78 ADRA1A (0.52) ADRA1AALDH1A1CYP3A4TSHRGAA
SCHEMBL9041741 0.78 ALDH1A1 (0.59) ADRA1AALDH1A1HSD17B10GAAKDM4E
SCHEMBL2061796 0.77 MEN1 (0.40) ADRA1ATSHRHSD17B10GAAMEN1
Hydrochloric Acid SCHEMBL9404913 0.77 ALDH1A1 (0.57) ADRA1AEP300KAT8ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL4821905 0.77 ACHE (0.35) ALDH1A1CYP3A4TDP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2701673-B1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'ORÉAL (FR) 2017-09-13 EP disclosed