SCHEMBL19337445

SCHEMBL19337445

N=N[C@@H](C(=O)O)c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.46
SLC7A5 Q01650 1/20 0.41
GRM8 O00222 1/20 0.38
GRM4 Q14833 1/20 0.38
ESR1 P03372 7/20 0.38
ESR2 Q92731 6/20 0.38
DRD1 P21728 2/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
TYR P14679 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28066129 0.76 SRC (0.43) SRCSLC7A5GRM8GRM4ESR1
Oxfenicine SCHEMBL652186 0.71 HSD17B10 (0.55) SRCSLC7A5GRM8GRM4ESR1
Oxfenicine SCHEMBL122315 0.71 HSD17B10 (0.55) SRCSLC7A5GRM8GRM4ESR1
Oxfenicine SCHEMBL124861 0.71 HSD17B10 (0.55) SRCSLC7A5GRM8GRM4ESR1
SCHEMBL7754587 0.70 SRC (0.64) SRCSLC7A5ESR1ESR2DRD1
SCHEMBL180939 0.70 SRC (0.54) SRCSLC7A5ESR1ESR2DRD1
SCHEMBL9701361 0.70 CYP2D6 (0.64) SRCSLC7A5ESR1ESR2DRD1
Oxfenicine SCHEMBL3492039 0.70 TDP1 (0.53) SRCSLC7A5GRM8GRM4ESR1
Oxfenicine SCHEMBL3500341 0.70 TDP1 (0.53) SRCSLC7A5GRM8GRM4ESR1
Oxfenicine SCHEMBL3492041 0.70 TDP1 (0.53) SRCSLC7A5GRM8GRM4ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2701673-B1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'ORÉAL (FR) 2017-09-13 EP disclosed