Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65952 | 0.81 | — | — | |
| SCHEMBL23572345 | 0.78 | CA1 (0.48) | HMBSAHRGAAKDM4ECYP1A2 | |
| SCHEMBL28896011 | 0.77 | HMBS (0.92) | HMBSACHELMNAMAPK8GAA | |
| SCHEMBL6561706 | 0.77 | — | — | |
| SCHEMBL8208273 | 0.77 | HMBS (0.92) | HMBSACHELMNAMAPK8GAA | |
| SCHEMBL8619374 | 0.77 | — | — | |
| SCHEMBL22537619 | 0.74 | MEN1 (0.41) | HMBSLMNAL3MBTL1MAPK8KDM4E | |
| SCHEMBL21763586 | 0.72 | HMBS (0.48) | HMBSTSHRACHEL3MBTL1AHR | |
| SCHEMBL28975482 | 0.71 | FKBP5 (0.43) | HMBSTSHRACHELMNAALOX12 | |
| Toluene SCHEMBL10976206 | 0.65 | ACHE (1.00) | TSHRACHELMNAALOX12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902489-B1 | FGFR3 FUSION GENE AND PHARMACEUTICAL DRUG TARGETING SAME | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-09-13 | — | — | EP | disclosed |