Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061520 | 0.76 | TAAR1 (0.41) | SKP2BACE1 | |
| SCHEMBL30279705 | 0.74 | CYP3A4 (0.41) | — | |
| SCHEMBL17196243 | 0.73 | LOXL2 (0.46) | — | |
| SCHEMBL27759345 | 0.73 | SKP2 (0.47) | SKP2BACE1 | |
| SCHEMBL28283960 | 0.72 | GAA (0.52) | — | |
| SCHEMBL10286692 | 0.70 | ALDH1A1 (0.38) | SKP2BACE1 | |
| SCHEMBL2037286 | 0.69 | CSNK2A1 (0.46) | SKP2BACE1 | |
| SCHEMBL27833864 | 0.69 | LOXL2 (0.36) | — | |
| SCHEMBL27813672 | 0.69 | PRSS1 (0.39) | — | |
| SCHEMBL27656591 | 0.69 | CYP3A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964223-B1 | COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY | MERCK SHARP & DOHME (US) | 2017-09-13 | — | — | EP | disclosed |