Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CCKBR | P32239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934409 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL28642718 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL28662843 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL29379056 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL31310810 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL5680135 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL504399 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL18207946 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL10843678 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 | |
| SCHEMBL4762341 | 1.00 | KDM4E (0.74) | KDM4ETSHRHSD17B10HTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142734-B | Preparation method and application of beta carboline compound intermediate | 京博农化科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-108969770-B | Dipeptide modified 1-methyl-3-hydroxymethyl-tetrahydro-beta-carboline, synthesis and application thereof | 首都医科大学 | 2021-07-27 | — | — | CN | claimed |
| CN-108948001-A | The synthetic route of 1R, 3S-1- methyl tetrahydro-beta-carboline -3- carboxylic acid, anti-thrombus activity and application | 首都医科大学 | 2018-12-07 | — | — | CN | claimed |
| US-8669267-B2 | Pharmaceutical, food or beverage having inhibitory activity on serotonin transporter | SUNTORY HOLDINGS LIMITED (JP) | 2014-03-11 | — | — | US | claimed |
| US-20110152309-A1 | PHARMACEUTICAL, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | SUNTORY HOLDINGS LIMITED (JP) | 2011-06-23 | — | — | US | claimed |
| EP-2332539-A1 | PHARMACEUTICAL PREPARATION, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | Suntory Holdings Limited (JP) | 2011-06-15 | — | — | EP | claimed |
| CN-113616646-B | Application of carboline alkaloid in preparation of anti-UVB radiation preparation | 中国科学院昆明植物研究所 | 2024-04-02 | — | — | CN | disclosed |
| EP-3501527-B1 | COMPOSITION FOR PREVENTING OR TREATING MENTAL DISORDER, CONTAININGLACTOBACILLUS | MD HEALTHCARE INC (KR) | 2024-03-06 | — | — | EP | disclosed |
| CN-111303148-B | 1-substituted beta-carboline derivatives and application thereof | 南京农业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-112142734-B | Preparation method and application of beta carboline compound intermediate | 京博农化科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-112142734-B | Preparation method and application of beta carboline compound intermediate | 京博农化科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| EP-3459950-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-18 | — | — | EP | disclosed |
| EP-3459951-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-11 | — | — | EP | disclosed |
| CN-102149383-A | Medicinal products or drinks and foods with serotonin transporter inhibiting activity | SUNTORY HOLDINGS LTD | 2011-08-10 | — | — | CN | disclosed |
| US-20110152309-A1 | PHARMACEUTICAL, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | SUNTORY HOLDINGS LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20110152309-A1 | PHARMACEUTICAL, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | SUNTORY HOLDINGS LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2332539-A1 | PHARMACEUTICAL PREPARATION, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | Suntory Holdings Limited (JP) | 2011-06-15 | — | — | EP | disclosed |
| JP-2008239585-A | AGENT FOR INHIBITING INCREASE OF BLOOD SUGAR LEVEL AT HUNGRY TIME AND AFTER MEAL, AND ANTIDIABETIC PHARMACEUTICAL | SAKAMOTO JOZO KK | 2008-10-09 | — | — | JP | disclosed |
| WO-2004113336-A1 | CARBOLINE AND BETACARBOLINE DERIVATIVES FOR USE AS HDAC ENZYME INHIBITORS | CHROMA THERAPEUTICS LIMITED (GB) | 2004-12-29 | — | — | WO | disclosed |
| US-4628057-A | Tetrahydro-β-carboline derivatives and treatment of liver diseases | TANABE SEIYAKU CO., LTD. (JP) | 1986-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152309-A1 | PHARMACEUTICAL, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER | SLC6A4, SLC6A3, HTR1A | KDM4E 3006/4885TSHR 1119/4885HSD17B10 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.