SCHEMBL19341883

SCHEMBL19341883

O=C1c2ccccc2C(=O)N1OP(=O)(ON1C(=O)c2ccccc2C1=O)c1ccc(-c2ccc(P(=O)(ON3C(=O)c4ccccc4C3=O)ON3C(=O)c4ccccc4C3=O)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.41
▸ ALDH1A1 P00352 7/20 0.39
▸ MAPT P10636 5/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ KDM4E B2RXH2 4/20 0.39
▸ HPGD P15428 3/20 0.39
▸ HTT P42858 2/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ CYP1A2 P05177 3/20 0.36
▸ VDR P11473 2/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ F2 P00734 2/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ XBP1 P17861 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19341894 0.89 ALDH1A1 (0.44) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL19341908 0.77 GAA (0.48) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL19341891 0.74 ELANE (0.45) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL19341904 0.73 GAA (0.46) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL11563803 0.68 GAA (0.44) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL19341895 0.68 SRC (0.47) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL20768726 0.67 GAA (0.56) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL262472 0.67 GAA (0.56) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL19341893 0.67 GAA (0.43) GAAALDH1A1MAPTKDM4EVDR
SCHEMBL2353516 0.66 ALDH1A1 (0.52) GAAALDH1A1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-01-28 — — US disclosed
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-14 — — US disclosed
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260366-A1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS AND/OR AS STABILIZERS FOR PLASTICS, FLAME-RETARDANT AND/OR STABILIZED PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS PFAS, FERMT2, PGM2 GAA 2459/4885ALDH1A1 1024/4885MAPT 21/4885
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings PFAS, FERMT2, PGM2 GAA 2459/4885ALDH1A1 1024/4885MAPT 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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