Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437401 | 0.91 | KMT2A (0.50) | KMT2AMEN1CA2PARP10ALDH1A1 | |
| SCHEMBL143772 | 0.84 | MEN1 (0.61) | KMT2AMEN1CA2CA12CA4 | |
| SCHEMBL5709288 | 0.83 | TPSAB1 (0.51) | KMT2AMEN1PRSS1PARP10ALDH1A1 | |
| SCHEMBL147245 | 0.83 | KMT2A (0.44) | KMT2AMEN1PARP10ALDH1A1LMNA | |
| SCHEMBL2756749 | 0.82 | KMT2A (0.47) | KMT2AMEN1CA2CA12CA1 | |
| SCHEMBL113937 | 0.81 | IDO1 (0.54) | KMT2AMEN1CA2CA1CA9 | |
| SCHEMBL2297635 | 0.81 | PARP10 (0.54) | CA2CA1CA9PARP10ALDH1A1 | |
| SCHEMBL21385042 | 0.81 | KMT2A (0.42) | KMT2AMEN1CA2CA1PARP10 | |
| SCHEMBL436380 | 0.81 | KMT2A (0.42) | KMT2AMEN1PRSS1CA2PARP10 | |
| SCHEMBL5762294 | 0.81 | MAOB (0.54) | KMT2AMEN1PARP10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521299-B | Pyrazolopyrimidine derivative or conjugate thereof, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118019750-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117838875-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115867319-B | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| WO-2023091957-A1 | PEPTIDE CONJUGATES OF PEPTIDIC TUBULIN INHIBITORS AS THERAPEUTICS | CYBREXA 4, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| CN-115867319-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114222590-A | Compositions, devices and methods for factor VII therapy | 西吉隆医疗股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-113840620-A | Compositions, devices and methods for treating fabry disease | 西吉隆医疗股份有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-113521299-A | Pyrazolopyrimidine derivative or conjugate thereof, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112203646-A | Implantable particles and related methods | 西吉隆医疗股份有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-112105612-A | Anti-fibrotic compounds, devices and uses thereof | 西吉隆医疗股份有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-111372612-A | Methods, compositions, and implantable elements comprising viable cells | 西吉隆医疗股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-110545814-A | Chemokine CXCR4 receptor modulators and uses related thereto | UNIV EMORY | 2019-12-06 | — | — | CN | disclosed |
| EP-2331518-A1 | NEW BRADYKININ B1 ANTAGONISTS | Evotec AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010020556-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC NEUROSCIENCES GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |