Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437401 | 0.91 | KMT2A (0.50) | MEN1KMT2APARP10ALDH1A1 | |
| Benzyl Carbamate SCHEMBL9998168 | 0.90 | ALDH1A1 (0.55) | LOXL2KMT2AMAOBALDH1A1 | |
| SCHEMBL143772 | 0.84 | MEN1 (0.61) | ABATMEN1KMT2AALDH1A1 | |
| SCHEMBL20109593 | 0.84 | ENPP2 (0.52) | LOXL2PLGALDH1A1 | |
| SCHEMBL23533686 | 0.83 | TAAR1 (0.54) | KMT2AMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL29264769 | 0.83 | TPSAB1 (0.51) | TPSAB1PRSS1TPSD1TPSG1ABAT | |
| SCHEMBL1934595 | 0.83 | KMT2A (0.44) | PRSS1MEN1KMT2APARP10ALDH1A1 | |
| SCHEMBL147245 | 0.83 | KMT2A (0.44) | LOXL2MEN1KMT2AMAOBPARP10 | |
| SCHEMBL21385042 | 0.81 | KMT2A (0.42) | MEN1KMT2APARP10ALDH1A1 | |
| SCHEMBL113937 | 0.81 | IDO1 (0.54) | MEN1KMT2AMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189440-A1 | TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| CN-115073467-B | Pyrimidine imidazole compound, and pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-03-15 | — | — | CN | disclosed |
| EP-4301417-A1 | TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES | The Research Foundation for The State University of New York (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |
| CN-117177958-A | Small molecule modulators of alveolar type 2cell proliferation for the treatment of pulmonary diseases | 斯克里普斯研究学院 | 2023-12-05 | — | — | CN | disclosed |
| CN-117042782-A | Multilayer structure using chemically crosslinked alginic acid | 持田制药株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-116940562-A | Acetamido-phenylbenzamide derivatives and methods of use thereof | 希华医药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-115836054-A | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-108770357-B | Polymer conjugate vaccines | 芝加哥大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-115209920-A | Thienoazepine immunoconjugates and uses thereof | 博尔特生物治疗药物有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114828894-A | Polymer-supported thienoazepine compounds and uses thereof | 博尔特生物治疗药物有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-113004283-A | Tetracyclic compounds as plasma kallikrein inhibitors and uses thereof | 成都康弘药业集团股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-113004286-A | Tricyclic compounds as plasma kallikrein inhibitors and uses thereof | 成都康弘药业集团股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-111386263-A | Modulation of chimeric antigen receptors | 达纳-法伯癌症研究所有限公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-107257800-B | Method for inducing target protein degradation by bifunctional molecules | 达纳-法伯癌症研究所股份有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-110621322-A | Modulatable endogenous protein degradation with heterobifunctional compounds | 达纳-法伯癌症研究所有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-109187940-A | The preparation and application of a kind of isotopic tag reagent for Analysis of polysaccharides | 南京谱利健生物技术有限公司 | 2019-01-11 | — | — | CN | disclosed |
| EP-1727790-A1 | PHENYLAMINOETHANOL DERIVATIVES AS BETA2 RECEPTOR AGONISTS | Pfizer Limited (GB) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005090288-A1 | PHENYLAMINOETHANOL DERIVATES AS BETA2 RECEPTOR AGONISTS | PFIZER LIMITED (GB) | 2005-09-29 | — | — | WO | disclosed |
| CN-1450915-A | Matrix metalloproteinase inhibitors as target components in diagnostic agents | BRISTOL MYERS SQUIBB CO (US) | 2003-10-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240189440-A1 | TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES | TLR7, TLR8, TLR9 | TPSAB1 934/4885PRSS1 3248/4885TPSD1 1272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.