SCHEMBL147245

SCHEMBL147245

NC(=O)OCc1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
CYP3A4 P08684 2/20 0.42
LMNA P02545 2/20 0.42
MAOA P21397 2/20 0.42
CYP1A2 P05177 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
GFER P55789 1/20 0.42
TSHR P16473 1/20 0.42
MAOB P27338 3/20 0.41
PARP10 Q53GL7 2/20 0.41
APP P05067 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
F2 P00734 1/20 0.40
PLAU P00749 1/20 0.40
PLAT P00750 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30437401 0.91 KMT2A (0.50) KMT2AMEN1LMNACYP1A2ALDH1A1
SCHEMBL932927 0.84 KMT2A (0.45) KMT2AMEN1CYP3A4LMNAMAOA
SCHEMBL143772 0.84 MEN1 (0.61) KMT2AMEN1LMNAALDH1A1L3MBTL1
SCHEMBL23533686 0.83 TAAR1 (0.54) KMT2ALMNACYP1A2ALDH1A1TDP1
SCHEMBL1934595 0.83 KMT2A (0.44) KMT2AMEN1LMNAALDH1A1TDP1
SCHEMBL5709288 0.83 TPSAB1 (0.51) KMT2AMEN1ALDH1A1MAOBPARP10
SCHEMBL25448604 0.83 KMT2A (0.44) KMT2AMEN1CYP3A4LMNAMAOA
SCHEMBL1561073 0.83 ALDH1A1 (0.45) KMT2AMEN1CYP3A4LMNAMAOA
SCHEMBL17080518 0.81 CYP3A4 (0.54) KMT2AMEN1CYP3A4PARP10APP
SCHEMBL2511445 0.81 ALDH1A1 (0.64) KMT2AMEN1CYP3A4LMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 760 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055169-A Anti-PSMA antibody drug conjugates comprising irinotecan ADC疗法责任有限公司 2026-05-15 CN claimed
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MED LTD (GB) 2026-05-07 US claimed
US-20260061066-A1 ANTI-GRP78 ANTIBODY, IMMUNOCONJUGATE AND USES THEREOF UCT BIOSCIENCE CO., LTD. (TW) 2026-03-05 US claimed
US-20260027241-A1 Near-Infrared Dyes And Conjugates For Targeting Tumors LAHJAVIDA, INC. (US) 2026-01-29 US claimed
US-20260021191-A1 TUMOR MICROENVIRONMENT-ACTIVATED CYTOKINE AND USE THEREOF YAFEI SHANGHAI BIOLOGY MEDICINE SCIENCE & TECH CO LTD (CN) 2026-01-22 US claimed
EP-4680644-A1 SACITUZUMAB DRUG CONJUGATES AND PREPARATION THEREOF Zydus Lifesciences Limited (IN) 2026-01-21 EP claimed
EP-4665770-A1 DARATUMUMAB DRUG CONJUGATES AND PREPARATION THEREOF Zydus Lifesciences Limited (IN) 2025-12-24 EP claimed
EP-4658690-A2 ANTI-CD180 BINDING MOLECULES AND USES THEREOF Corellia AI (US) 2025-12-10 EP claimed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US claimed
EP-4646233-A1 HER3-BINDING ANTIBODY-DRUG CONJUGATE Hummingbird Bioscience Pte. Ltd. (SG) 2025-11-12 EP claimed
US-10335501-B2 Cyclic peptides with enhanced nerve-binding selectively, nanoparticles bound with said cyclic peptides, and use of same for real-time in vivo nerve tissue imaging MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2019-07-02 US claimed
US-10287564-B2 Procoagulant compounds BIOVERATIV THERAPEUTICS INC. (US) 2019-05-14 US claimed
US-20190070310-A1 NANOPARTICLE DRUG CONJUGATES MEMORIAL SLOAN KETTERING CANCER CENTER 2019-03-07 US claimed
US-10111963-B2 Nanoparticle drug conjugates MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2018-10-30 US claimed
US-20160166714-A1 CYCLIC PEPTIDES WITH ENHANCED NERVE-BINDING SELECTIVELY, NANOPARTICLES BOUND WITH SAID CYCLIC PEPTIDES, AND USE OF SAME FOR REAL-TIME IN VIVO NERVE TISSUE IMAGING MEMORIAL SLOAN KETTERING CANCER CENTER 2016-06-16 US claimed
US-20150343091-A1 NANOPARTICLE DRUG CONJUGATES MEMORIAL SLOAN KETTERING CANCER CENTER 2015-12-03 US claimed
US-20150184142-A1 PROCOAGULANT COMPOUNDS BIOGEN IDEC MA INC. (US) 2015-07-02 US claimed
EP-2858659-A1 PROCOAGULANT COMPOUNDS Biogen Idec MA Inc. (US) 2015-04-15 EP claimed
US-8796229-B2 Feedback prodrug UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2014-08-05 US claimed
WO-2013185113-A1 PROCOAGULANT COMPOUNDS BIOGEN IDEC MA INC. (US) 2013-12-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 KMT2A 718/4885MEN1 383/4885CYP3A4 1533/4885
US-20260125418-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT BRCA1, L3MBTL1, LMNA KMT2A 3488/4885MEN1 35/4885CYP3A4 1802/4885
US-10287564-B2 Procoagulant compounds PLG, F2, PLAT KMT2A 3722/4885MEN1 1483/4885CYP3A4 1524/4885
US-20260021191-A1 TUMOR MICROENVIRONMENT-ACTIVATED CYTOKINE AND USE THEREOF IFNG, IFNAR1, STAT1 KMT2A 2390/4885MEN1 2090/4885CYP3A4 3615/4885
US-20150184142-A1 PROCOAGULANT COMPOUNDS PLG, F2, PLAT KMT2A 3722/4885MEN1 1483/4885CYP3A4 1524/4885
US-20260061066-A1 ANTI-GRP78 ANTIBODY, IMMUNOCONJUGATE AND USES THEREOF IGSF11, DNAJC10, HSPA5 KMT2A 3849/4885MEN1 4354/4885CYP3A4 4803/4885
US-20260027241-A1 Near-Infrared Dyes And Conjugates For Targeting Tumors ADAMTS1, ADAMTS4, ADAMTS5 KMT2A 3222/4885MEN1 2366/4885CYP3A4 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.