Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19332211 | 0.82 | ALDH1A1 (0.66) | ALDH1A1GAADHFRTSHRSMN1; SMN2 | |
| SCHEMBL19332656 | 0.78 | ALDH1A1 (0.49) | ALDH1A1GAADHFRTSHRSMN1; SMN2 | |
| SCHEMBL19346086 | 0.74 | GAA (0.67) | ALDH1A1GAATSHRTDP1LMNA | |
| SCHEMBL19346083 | 0.74 | GAA (0.60) | ALDH1A1GAATSHRTDP1LMNA | |
| SCHEMBL19332621 | 0.74 | DHFR (0.68) | ALDH1A1DHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL14478907 | 0.73 | FBP1 (0.68) | ALDH1A1DHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL23467914 | 0.72 | GAA (0.69) | ALDH1A1GAATSHRTDP1LMNA | |
| SCHEMBL9237237 | 0.72 | ALDH1A1 (1.00) | ALDH1A1DHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL15650208 | 0.72 | ALDH1A1 (0.69) | ALDH1A1GAADHFRTSHRSMN1; SMN2 | |
| SCHEMBL19332345 | 0.72 | NPC1 (0.41) | ALDH1A1SMN1; SMN2TDP1MMP2ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |