Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103894 | 0.74 | HTR2C (0.53) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL17375448 | 0.73 | — | — | |
| SCHEMBL12584607 | 0.73 | HTR2C (0.46) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL1934008 | 0.73 | HTR2C (0.46) | HTR2CL3MBTL1SYKTRIM24 | |
| SCHEMBL24386932 | 0.72 | HTR2C (0.50) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL5477688 | 0.72 | NUDT1 (0.55) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL9970925 | 0.72 | HTR2C (0.50) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL19865160 | 0.72 | L3MBTL1 (0.53) | HTR2CL3MBTL1NUDT1SYK | |
| SCHEMBL1934651 | 0.71 | HTR2C (0.50) | HTR2CL3MBTL1NUDT1 | |
| SCHEMBL19616550 | 0.70 | HTR2C (0.43) | HTR2CL3MBTL1TRIM24CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509602-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | Cylene Pharmaceuticals, Inc. (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011068667-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |