SCHEMBL1934693

SCHEMBL1934693

CCOC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.77
MEN1 O00255 1/20 0.68
ABL1 P00519 1/20 0.68
LMNA P02545 1/20 0.68
PKM P14618 1/20 0.68
IDE P14735 1/20 0.68
MAPK1 P28482 1/20 0.68
KMT2A Q03164 1/20 0.68
RIN1 Q13671 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
HLCS P50747 6/20 0.65
HPSE Q9Y251 1/20 0.55
F2 P00734 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
TPSAB1 Q15661 1/20 0.52
CNR1 P21554 3/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12050324 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL10124218 0.90 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL10854861 0.90 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL7157942 0.90 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL9912047 0.89 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL10854680 0.89 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
SCHEMBL22290232 0.88 TDP1 (0.82) TDP1MEN1ABL1LMNAPKM
SCHEMBL14410158 0.88 TDP1 (0.73) TDP1MEN1ABL1LMNAPKM
SCHEMBL10389671 0.87 HLCS (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL2322596 0.87 HLCS (0.71) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113322041-B Thermosetting aqueous polyurethane adhesive and preparation method and application thereof 霍山真之木新材料科技有限公司 2023-10-10 CN claimed
CN-113322041-A Thermosetting water-based polyurethane adhesive and preparation method and application thereof 霍山真之木新材料科技有限公司 2021-08-31 CN claimed
CN-112451415-A Anti-drying moisturizing sun screen and preparation method thereof 黄国威 2021-03-09 CN claimed
CN-111265442-A Skin care composition and application thereof 上海科颜生物科技有限公司 2020-06-12 CN claimed
US-9913789-B2 Formulations containing sphinganine EVONIK DEGUSSA GMBH (DE) 2018-03-13 US claimed
US-9445992-B2 Mucosal delivery compositions comprising a peptide complexed with a crown compound and/or a counter ion ARISGEN SA (CH) 2016-09-20 US claimed
CN-102770152-B The mucosal delivery of peptides 阿瑞斯根股份有限公司 2016-07-06 CN claimed
US-20160184204-A1 FORMULATIONS CONTAINING SPHINGANINE EVONIK DEGUSSA GMBH (DE) 2016-06-30 US claimed
CN-105579020-A Formulations containing sphinganine EVONIK DEGUSSA GMBH 2016-05-11 CN claimed
US-20120302502-A1 MUCOSAL DELIVERY COMPOSITIONS COMPRISING A PEPTIDE COMPLEXED WITH A CROWN COMPOUND AND/OR A COUNTER ION ARISGEN SA (CH) 2012-11-29 US claimed
CN-102770152-A Mucosal delivery of peptides ARISGEN SA 2012-11-07 CN claimed
EP-2504019-A2 MUCOSAL DELIVERY COMPOSITION COMPRISING A PEPTIDE COMPLEXED WITH A CROWN COMPOUND AND/OR A COUNTER ION ArisGen SA (CH) 2012-10-03 EP claimed
WO-2011064316-A2 MUCOSAL DELIVERY OF PEPTIDES BOTTI PAOLO (CH) 2011-06-03 WO claimed
EP-0081771-B1 HETEROCYCLIC COMPOUNDS, THEIR PREPARATION, COSMETIC PREPARATIONS CONTAINING THEM AND THEIR USE IN HAIR AND SKIN CARE Richardson-Vicks, Inc. (US) 1986-05-28 EP claimed
US-4584191-A Hair care and skin care compositions containing biotin ethyl ester HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US claimed
WO-2025119790-A1 COMPOSITION COMPRISING CERAMIDE AND TRIGLYCERIDE EVONIK OPERATIONS GMBH (DE) 2025-06-12 WO disclosed
CN-113322041-B Thermosetting aqueous polyurethane adhesive and preparation method and application thereof 霍山真之木新材料科技有限公司 2023-10-10 CN disclosed
US-5952373-A APPLYING TO THE SKIN AN EFFECTIVE AMOUNT OF ONE OR MORE FLAVONOIDS BEIERSDORF AG (DE) 1999-09-14 US disclosed
US-4584191-A Hair care and skin care compositions containing biotin ethyl ester HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US disclosed
US-4584191-A Hair care and skin care compositions containing biotin ethyl ester HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302502-A1 MUCOSAL DELIVERY COMPOSITIONS COMPRISING A PEPTIDE COMPLEXED WITH A CROWN COMPOUND AND/OR A COUNTER ION VIP, CFTR, IAPP TDP1 3594/4885MEN1 1086/4885ABL1 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.