Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19368218 | 0.88 | HTR7 (0.47) | ALDH1A1CYP3A4SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL19347238 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP3A4SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL2761731 | 0.83 | SMN1; SMN2 (0.52) | ALDH1A1CYP3A4SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL19347247 | 0.82 | KDM4E (0.41) | ALDH1A1CYP3A4SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL15702727 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP3A4HTR7MTNR1AMTNR1B | |
| SCHEMBL6048258 | 0.81 | HTR7 (0.54) | ALDH1A1CYP3A4HTR7 | |
| SCHEMBL15702714 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HTR7MTNR1AMTNR1B | |
| SCHEMBL9170532 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL14619944 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPK1KMT2ATDP1 | |
| SCHEMBL13086504 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1CYP3A4SMN1; SMN2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3219712-B1 | COUMARIN DYES AND CONJUGATES THEREOF | CYANAGEN SRL (IT) | 2021-08-18 | — | — | EP | disclosed |
| EP-3219712-B1 | COUMARIN DYES AND CONJUGATES THEREOF | CYANAGEN SRL (IT) | 2021-08-18 | — | — | EP | disclosed |
| US-10160861-B2 | Coumarin dyes and conjugates thereof | CYANAGEN S.R.L. (IT) | 2018-12-25 | — | — | US | disclosed |
| US-20170267866-A1 | NOVEL COUMARIN DYES AND CONJUGATES THEREOF | CYANAGEN S.R.L. (IT) | 2017-09-21 | — | — | US | disclosed |
| US-20170267866-A1 | NOVEL COUMARIN DYES AND CONJUGATES THEREOF | CYANAGEN S.R.L. (IT) | 2017-09-21 | — | — | US | disclosed |
| US-20170267866-A1 | NOVEL COUMARIN DYES AND CONJUGATES THEREOF | CYANAGEN S.R.L. (IT) | 2017-09-21 | — | — | US | disclosed |
| EP-3219712-A1 | COUMARIN DYES AND CONJUGATES THEREOF | Cyanagen Srl (IT) | 2017-09-20 | — | — | EP | disclosed |
| EP-3219712-A1 | COUMARIN DYES AND CONJUGATES THEREOF | Cyanagen Srl (IT) | 2017-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160861-B2 | Coumarin dyes and conjugates thereof | IK, CYP3A7, CYP7A1 | ALDH1A1 93/4885CYP3A4 12/4885SMN1; SMN2 4667/4885 |
| US-20170267866-A1 | NOVEL COUMARIN DYES AND CONJUGATES THEREOF | IK, CYP3A7, HCCS | ALDH1A1 89/4885CYP3A4 19/4885SMN1; SMN2 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.