Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350969 | 0.89 | PLCD1 (0.51) | TDP1PLCD1F2PRSS1PRSS2 | |
| Ammonia Solution, Strong SCHEMBL29662377 | 0.89 | PLCD1 (0.50) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL19350967 | 0.84 | TDP1 (0.47) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL20656160 | 0.81 | TDP1 (0.55) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL22600908 | 0.80 | HLCS (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| Geranyl Diphosphate SCHEMBL19329153 | 0.77 | TDP1 (0.56) | TDP1PLCD1MEN1ABL1LMNA | |
| SCHEMBL20306213 | 0.76 | PLCD1 (0.65) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL12672576 | 0.75 | TDP1 (0.63) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL18751368 | 0.74 | PLCD1 (0.75) | TDP1PLCD1F2PRSS1PRSS2 | |
| SCHEMBL13110899 | 0.73 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153774-A1 | PRENYLATION ASSAY | NIGHTSTARX LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |