Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 3/20 | 0.59 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656160 | 0.93 | TDP1 (0.55) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL22493325 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL13045403 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL12320610 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL7376597 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL15870672 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL12729936 | 0.83 | HLCS (0.71) | HLCSCNR1CNR2TDP1MEN1 | |
| SCHEMBL12672576 | 0.83 | TDP1 (0.63) | HLCSCNR1TDP1MEN1ABL1 | |
| SCHEMBL19350969 | 0.82 | PLCD1 (0.51) | CNR1CNR2TDP1MEN1ABL1 | |
| SCHEMBL8240579 | 0.82 | TDP1 (0.72) | HLCSCNR1CNR2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200341015-A1 | PRENYLATION ASSAY | NIGHTSTARX LTD. (GB) | 2020-10-29 | — | — | US | disclosed |