Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCD1 | P51178 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 3/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350969 | 0.99 | PLCD1 (0.51) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL19350968 | 0.89 | TDP1 (0.48) | PLCD1TDP1F2PRSS1PRSS2 | |
| Geranyl Diphosphate SCHEMBL19329153 | 0.86 | TDP1 (0.56) | PLCD1TDP1MEN1ABL1LMNA | |
| SCHEMBL20656160 | 0.83 | TDP1 (0.55) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL22600908 | 0.82 | HLCS (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19350967 | 0.80 | TDP1 (0.47) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL12672576 | 0.76 | TDP1 (0.63) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13110899 | 0.75 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 | |
| Biotin SCHEMBL7845644 | 0.73 | TDP1 (0.77) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL20306213 | 0.73 | PLCD1 (0.65) | PLCD1TDP1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109072281-B | Prenylation assay | 夜星有限公司 | 2023-07-25 | — | — | CN | claimed |
| EP-3429569-B1 | METHODS FOR PREVENTING OR TREATING PARKINSON'S DISEASE BY THE FARNESYLATION OF PARIS | UNIV JOHNS HOPKINS (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-109072281-B | Prenylation assay | 夜星有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20230012209-A1 | METHODS OF PREVENTING OR TREATING PARKINSON'S DISEASE BY THE FARNESYLATION OF PARIS | THE JOHNS HOPKINS UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
| WO-2022109247-A1 | VIRAL VECTOR POTENCY ASSAY | BIOGEN MA INC. (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012209-A1 | METHODS OF PREVENTING OR TREATING PARKINSON'S DISEASE BY THE FARNESYLATION OF PARIS | PINK1, PGC, SNCA | PLCD1 3641/4885TDP1 1926/4885F2 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.