Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381230 | 1.00 | TDP1 (0.44) | TDP1KMT2AL3MBTL1ALDH1A1MAPT | |
| Undecane SCHEMBL28372274 | 0.96 | GPR84 (0.43) | TDP1KMT2AL3MBTL1ALDH1A1PPARG | |
| SCHEMBL380743 | 0.93 | GAA (0.45) | TDP1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL9084120 | 0.92 | KMT2A (0.40) | TDP1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3294519 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL380519 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL8376531 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL9633625 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL3918719 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG | |
| SCHEMBL165415 | 0.91 | FDPS (0.45) | TDP1KMT2AALDH1A1GAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908747-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXYBUTYRIC ESTER | KOWA CO (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-7767845-B2 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | KOWA CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7582791-B2 | Process for producing optically active ester | KOWA CO., LTD. (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20090209780-A1 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | KOWA CO., LTD. (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090118535-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ESTER | KOWA CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-4060691-A | 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters | G. D. SEARLE & CO. (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118535-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ESTER | CYP8B1, HACL2, ACSL3 | TDP1 4528/4885KMT2A 4285/4885L3MBTL1 1914/4885 |
| US-20090209780-A1 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | CYP4X1, AGL, HACL2 | TDP1 4594/4885KMT2A 1229/4885L3MBTL1 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.