Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553690 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL3452192 | 0.74 | CYP1A2 (0.56) | MEN1KMT2ANPC1MAPK1KDM4E | |
| SCHEMBL857880 | 0.72 | AURKA (0.70) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL4951590 | 0.69 | NPC1 (0.36) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL15864563 | 0.69 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL717594 | 0.69 | GAA (0.42) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL14869497 | 0.68 | GAA (0.43) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL14869535 | 0.68 | CA12 (0.39) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL5849398 | 0.68 | NPC1 (0.49) | MEN1KMT2ARAB9AGAANPC1 | |
| SCHEMBL20771413 | 0.68 | ABL1 (0.53) | KMT2ARAB9ANPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | BAYERCROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | TYMP, TYMS, TPMT | MEN1 2405/4885KMT2A 2302/4885RAB9A 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.