Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.41 |
| ▸ | RAB9A | P51151 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951590 | 0.83 | NPC1 (0.36) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL1935183 | 0.80 | MEN1 (0.38) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL717594 | 0.78 | GAA (0.42) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL7720808 | 0.78 | NPC1 (0.61) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL7254231 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL14869497 | 0.74 | GAA (0.43) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL14869535 | 0.74 | CA12 (0.39) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL28318668 | 0.71 | GLO1 (0.56) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL14869496 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KMT2AGAAKDM4ELMNA | |
| SCHEMBL2174053 | 0.69 | ALDH1A1 (0.53) | ALDH1A1NPC1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | claimed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | claimed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-24 | — | — | US | disclosed |
| EP-2486031-A2 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2012-08-15 | — | — | EP | disclosed |
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | BAYERCROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | BAYERCROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | BAYERCROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| CN-102203086-A | Thienylamino pyrimidines for use as fungicides | BAYER CROPSCIENCE AG | 2011-09-28 | — | — | CN | disclosed |
| CN-102203086-A | Thienylamino pyrimidines for use as fungicides | BAYER CROPSCIENCE AG | 2011-09-28 | — | — | CN | disclosed |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-2331532-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2011042389-A2 | PHENYLPYRI(MI)DINYLAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | WO | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010025851-A1 | THIENYLAMINO PYRIMIDINES FOR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237612-A1 | Thienylamino pyrimidines for use as Fungicides | TYMP, TYMS, TPMT | ALDH1A1 805/4885NPC1 4603/4885MEN1 2405/4885 |
| US-20130281455-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ALDH1A1 516/4885NPC1 3221/4885MEN1 1254/4885 |
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | ALDH1A1 516/4885NPC1 3221/4885MEN1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.