Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 12/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.56 |
| ▸ | TSHR | P16473 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.51 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.51 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909931 | 0.81 | HDAC3 (0.58) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3452402 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3451695 | 0.74 | ALDH1A1 (0.50) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL1935183 | 0.74 | MEN1 (0.38) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL29836535 | 0.73 | ATM (0.55) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL10441707 | 0.73 | ATM (0.55) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5940015 | 0.71 | HDAC3 (0.55) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3976219 | 0.71 | MAOA (0.54) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL2719597 | 0.71 | TSHR (0.49) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL23093434 | 0.71 | ALDH1A1 (0.49) | CYP1A2CYP2D6ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| EP-1753735-A1 | SUBSTITUTED THIAZOLE AND PYRIMIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | Transtech Pharma, Inc. (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | disclosed |
| WO-2005103022-A1 | SUBSTITUTED THIAZOLE AND PYRIMIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR MODULATORS | TRANSTECH PHARMA, INC. (US) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | CYP1A2 261/4885CYP2D6 328/4885ALDH1A1 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.