Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.45 |
| ▸ | CDK1 | P06493 | 7/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.45 |
| ▸ | CDK9 | P50750 | 6/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | BMPR2 | Q13873 | 5/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935605 | 0.80 | CDK2 (0.42) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL994027 | 0.79 | SYK (0.45) | CDK2CDK5CCNA2CDK5R1SYK | |
| SCHEMBL1935341 | 0.78 | TBK1 (0.38) | CDK2CDK1CCNB1CCNE1CDK5 | |
| SCHEMBL2505615 | 0.76 | BRD4 (0.51) | CDK2CDK1CCNT1CCNB1CDK9 | |
| SCHEMBL1937021 | 0.74 | SYK (0.44) | BMPR2TBK1NTRK1IKBKESYK | |
| SCHEMBL1773861 | 0.73 | CCNA2 (0.49) | CDK2CDK1CCNB1CCNA2FLT3 | |
| SCHEMBL1934514 | 0.72 | SYK (0.37) | CDK2CDK5CCNA2CDK5R1BMPR2 | |
| SCHEMBL1936329 | 0.72 | BRD4 (0.39) | CDK2CDK1CCNT1CCNB1CDK9 | |
| SCHEMBL24805489 | 0.71 | CDK5 (0.48) | CDK2CDK1CCNB1CDK5CCNA2 | |
| SCHEMBL2507666 | 0.71 | RAB9A (0.39) | CDK2CDK1CCNB1CCNE1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331512-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |