Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.36 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 2/20 | 0.35 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | SIK1 | P57059 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.35 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935605 | 0.79 | CDK2 (0.42) | TBK1PDPK1CDK5CDK5R1SYK | |
| SCHEMBL994027 | 0.78 | SYK (0.45) | CDK5CDK5R1SYKEGFRCDK2 | |
| SCHEMBL1935232 | 0.78 | CDK2 (0.45) | TBK1PDPK1CDK5CDK5R1SYK | |
| SCHEMBL2509244 | 0.76 | CTSC (0.48) | SYKNTRK1 | |
| SCHEMBL1937021 | 0.73 | SYK (0.44) | TBK1PDPK1SYKNTRK1IKBKE | |
| SCHEMBL1773861 | 0.73 | CCNA2 (0.49) | TBK1PDPK1SYKNTRK1IKBKE | |
| SCHEMBL1934514 | 0.71 | SYK (0.37) | TBK1PDPK1CDK5CDK5R1SYK | |
| SCHEMBL24805489 | 0.71 | CDK5 (0.48) | TBK1CDK5CDK5R1NTRK1IKBKE | |
| SCHEMBL2507666 | 0.70 | RAB9A (0.39) | TBK1SYKULK1ULK2CDK2 | |
| SCHEMBL1935695 | 0.69 | SYK (0.39) | TBK1PDPK1CDK5CDK5R1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| EP-2331512-A1 | ALKOXY-SUBSTITUTED AND ALKYLTHIO-SUBSTITUTED ANILINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | HAX1, AGPS, PYM1 | TBK1 1405/4885PDPK1 2500/4885CDK5 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.