Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 2/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948716 | 1.00 | PRSS1 (0.37) | PRSS1CTSGCTRB1CMA1SPHK2 | |
| SCHEMBL19536294 | 1.00 | PRSS1 (0.37) | PRSS1CTSGCTRB1CMA1SPHK2 | |
| SCHEMBL19027138 | 1.00 | PRSS1 (0.37) | PRSS1CTSGCTRB1CMA1SPHK2 | |
| SCHEMBL17972405 | 0.89 | PRSS1 (0.39) | PRSS1CTSGCTRB1CMA1CSNK1E | |
| SCHEMBL15948554 | 0.86 | CTSK (0.43) | — | |
| SCHEMBL15948723 | 0.85 | PRSS1 (0.40) | PRSS1CTSGCTRB1CMA1MLYCD | |
| SCHEMBL20830060 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL17976925 | 0.81 | CSNK1E (0.40) | PRSS1CTSGCTRB1CMA1SPHK1 | |
| SCHEMBL12055826 | 0.79 | CSNK1E (0.44) | PRSS1CTSGCTRB1CMA1SPHK1 | |
| SCHEMBL14994792 | 0.78 | CSNK1E (0.48) | PRSS1CTSGCTRB1CMA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189978-A1 | ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2017-11-02 | — | — | WO | disclosed |
| WO-2017155923-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2017-09-14 | — | — | WO | disclosed |