Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084675 | 0.93 | L3MBTL1 (0.97) | L3MBTL1KDM4EGAAPKMSMN1; SMN2 | |
| SCHEMBL19354714 | 0.88 | L3MBTL1 (0.80) | L3MBTL1KDM4EGAAPKMSMN1; SMN2 | |
| SCHEMBL19321948 | 0.85 | L3MBTL1 (0.61) | L3MBTL1KDM4EGAAPKMSMN1; SMN2 | |
| SCHEMBL11985694 | 0.82 | L3MBTL1 (0.57) | L3MBTL1KDM4EPKMSMN1; SMN2TSHR | |
| SCHEMBL29735083 | 0.82 | L3MBTL1 (0.57) | L3MBTL1KDM4EPKMSMN1; SMN2TSHR | |
| SCHEMBL29735103 | 0.82 | L3MBTL1 (0.57) | L3MBTL1KDM4EPKMSMN1; SMN2TSHR | |
| SCHEMBL29735129 | 0.82 | L3MBTL1 (0.57) | L3MBTL1KDM4EPKMSMN1; SMN2TSHR | |
| SCHEMBL10084676 | 0.81 | L3MBTL1 (0.77) | L3MBTL1KDM4ETSHRHPGDNPSR1 | |
| SCHEMBL17213613 | 0.80 | L3MBTL1 (0.75) | L3MBTL1KDM4ETSHRHPGDNPSR1 | |
| SCHEMBL19317331 | 0.80 | L3MBTL1 (0.55) | L3MBTL1KDM4EGAAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |