Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354883 | 0.90 | PDE4D (0.46) | FKBP1ACYP2D6PDE4DSCN1ASCN2A | |
| SCHEMBL19354556 | 0.86 | FKBP1A (0.38) | FKBP1ACYP2D6HTR7SCN1ASCN2A | |
| SCHEMBL19322233 | 0.84 | SCN1A (0.43) | CYP2D6SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19321925 | 0.84 | PTPN1 (0.44) | HTR7SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19354671 | 0.83 | SCN1A (0.46) | CYP2D6HTR7SCN1ASCN2ASCN3A | |
| SCHEMBL19321980 | 0.80 | SCN1A (0.63) | CYP2D6HTR7SCN1ASCN2ASCN3A | |
| SCHEMBL19354676 | 0.80 | PTPN1 (0.41) | TDP1CYP2D6HTR7SCN1ASCN2A | |
| SCHEMBL19322079 | 0.78 | SCN1A (0.53) | HTR7SCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19317312 | 0.78 | HTR7 (0.39) | CYP2D6HTR7PDE4DSCN1ASCN2A | |
| SCHEMBL28403096 | 0.77 | TDP1 (0.46) | FKBP1ATDP1PLA2G1BATG4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |