Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321926 | 0.87 | KMT2A (0.40) | CYP2D6KMT2AMEN1CYP2C19HTR3E | |
| SCHEMBL19354548 | 0.86 | FKBP1A (0.40) | FKBP1ACYP2D6KMT2AMEN1CYP2C19 | |
| SCHEMBL19354671 | 0.84 | SCN1A (0.46) | CYP2D6KMT2AMEN1CYP2C19HTR3E | |
| SCHEMBL19317301 | 0.81 | HTR7 (0.37) | CYP2D6KMT2AMEN1CYP2C19HTR3E | |
| SCHEMBL19354883 | 0.80 | PDE4D (0.46) | FKBP1ACYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL19322233 | 0.77 | SCN1A (0.43) | CYP2D6KMT2AMEN1SCN1ASCN2A | |
| SCHEMBL19322079 | 0.76 | SCN1A (0.53) | KMT2AMEN1HTR7SCN1ASCN2A | |
| SCHEMBL19321980 | 0.76 | SCN1A (0.63) | CYP2D6KMT2AMEN1CYP2C19HTR3E | |
| SCHEMBL19321925 | 0.71 | PTPN1 (0.44) | KMT2AHTR7SCN1ASCN2ASCN3A | |
| SCHEMBL28403096 | 0.70 | TDP1 (0.46) | FKBP1AKMT2AMEN1CYP1A2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |