Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL31652342 | 0.85 | USP2 (0.50) | TSHRUSP2TDP1CA2CA1 | |
| SCHEMBL14285857 | 0.85 | USP2 (0.50) | TSHRUSP2TDP1CA2CA1 | |
| SCHEMBL6232266 | 0.83 | MGAM (0.38) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL29431009 | 0.82 | USP2 (0.39) | TSHRUSP2CA2CA1MAPK1 | |
| SCHEMBL3964956 | 0.82 | CA2 (0.57) | TSHRUSP2ALDH1A1CA2CA1 | |
| Acetoacetic Acid SCHEMBL939347 | 0.82 | CA4 (0.36) | TSHRUSP2ALDH1A1TDP1MGAM | |
| SCHEMBL28339815 | 0.82 | CA4 (0.36) | TSHRUSP2ALDH1A1TDP1MGAM | |
| SCHEMBL22431437 | 0.80 | USP2 (0.34) | TSHRUSP2CA2CA1KDM4E | |
| SCHEMBL2494024 | 0.79 | HDAC1 (0.50) | TSHRALDH1A1TDP1MGAMGAA | |
| Acetic Acid SCHEMBL8992551 | 0.79 | TSHR (0.41) | TSHRUSP2TDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024330-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | US | disclosed |
| EP-4203964-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022046905-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| EP-2735581-B1 | COMPOSITION AND POLYMER | ASAHI CHEMICAL IND (JP) | 2021-07-14 | — | — | EP | disclosed |
| US-9738757-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160222168-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-08-04 | — | — | US | disclosed |
| US-9334371-B2 | Composition and polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| US-8808954-B2 | Electrophotographic photoconductor, process cartridge including the same, and image forming apparatus including the same | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2014-08-19 | — | — | US | disclosed |
| EP-2735581-A1 | COMPOSITION AND POLYMER | Asahi Kasei Chemicals Corporation (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-20140121293-A1 | Composition and Polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2014-05-01 | — | — | US | disclosed |
| US-20120288300-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PROCESS CARTRIDGE INCLUDING THE SAME, AND IMAGE FORMING APPARATUS INCLUDING THE SAME | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20110177259-A1 | METHOD FOR MANUFACTURING OPTICAL WAVEGUIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2333596-A1 | METHOD FOR MANUFACTURING OPTICAL WAVEGUIDE | Nissan Chemical Industries, Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-6723487-B2 | Method for producing article coated with patterned film and photosensitive composition | NIPPON SHEET GLASS CO., LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20020160298-A1 | Method for producing article coated with patterned film and photosensitive composition | MINAMI, TSUTOMU (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1160625-A1 | METHOD FOR PRODUCING ARTICLE COATED WITH PATTERNED FILM AND PHOTOSENSITIVE COMPOSITION | Nippon Sheet Glass Co., Ltd. (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-4150105-A | 3-Ketosteroid antigenic conjugates, their preparation, antibodies and use | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4061604-A | 3-HYDROXY-5-PHOSPHONO-1,2-OXAPHOSPHOLANES | CIBA-GEIGY CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4051229-A | REDUCTION OF ALKALI OR ALKALINE EARTH CHLORATE IN SULFURIC OR HYDROCHLORIC ACID WITH COMPLEX B-DIKETONE-PALLADIUM CATALYST | THE JAPAN CARLIT CO., LTD. (JA) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240024330-A1 | CRF RECEPTOR ANTAGONISTS AND METHODS OF USE | CRHR1, CRHR2, MC2R | TSHR 161/4885USP2 3381/4885ALDH1A1 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.