Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 5/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276013 | 0.71 | SGPL1 (0.42) | SGPL1LAP3SMPD1FDPSS1PR2 | |
| SCHEMBL28693363 | 0.70 | OPRM1 (0.46) | SGPL1LAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL28685635 | 0.70 | OPRM1 (0.46) | SGPL1LAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL28680848 | 0.70 | OPRM1 (0.46) | SGPL1LAP3S1PR2S1PR1S1PR3 | |
| SCHEMBL19642501 | 0.70 | SGPL1 (0.48) | SGPL1LAP3SMPD1FDPSS1PR2 | |
| SCHEMBL15922973 | 0.69 | CA1 (0.35) | SGPL1FDPS | |
| SCHEMBL22491750 | 0.69 | SGPL1 (0.49) | SGPL1LAP3FDPS | |
| SCHEMBL14920031 | 0.69 | SGPL1 (0.49) | SGPL1LAP3FDPS | |
| SCHEMBL30286353 | 0.68 | SMPD1 (0.39) | LAP3SMPD1FDPSS1PR2S1PR1 | |
| SCHEMBL30965148 | 0.68 | SGPL1 (0.51) | SGPL1LAP3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12453762-B2 | Complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for treatment of glioblastoma | AMAL THERAPEUTICS SA (CH) | 2025-10-28 | — | — | US | disclosed |
| US-20250297282-A1 | VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE | JUNO THERAPEUTICS GMBH (DE) | 2025-09-25 | — | — | US | disclosed |
| US-12220450-B2 | Complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for treatment of colorectal cancer | AMAL THERAPEUTICS SA (CH) | 2025-02-11 | — | — | US | disclosed |
| US-12220387-B2 | Fusion comprising a cell penetrating peptide, a multi epitope and a TLR peptide agonist for treatment of cancer | AMAL THERAPEUTICS SA (CH) | 2025-02-11 | — | — | US | disclosed |
| US-12214048-B2 | Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist for use in medicine | AMAL THERAPEUTICS SA (CH) | 2025-02-04 | — | — | US | disclosed |
| US-12178788-B2 | Complex comprising a cell penetrating peptide, a cargo and a TLR peptide agonist | AMAL THERAPEUTICS SA (CH) | 2024-12-31 | — | — | US | disclosed |
| US-20240180150-A1 | Green Closed Loop Bio-waste Refining Process For Producing Smart Active Extracts and Delivery Systems for Their Application | CELLACURE LLC (US) | 2024-06-06 | — | — | US | disclosed |
| EP-3515476-B1 | FUSION COMPRISING A CELL PENETRATING PEPTIDE, A MULTIEPITOPE AND A TLR PEPTIDE AGONIST FOR TREATMENT OF CANCER | AMAL THERAPEUTICS SA (CH) | 2024-05-22 | — | — | EP | disclosed |
| EP-3693009-B1 | A NOVEL COMPLEX COMPRISING A CELL PENETRATING PEPTIDE, A CARGO AND A TLR PEPTIDE AGONIST FOR TREATMENT OF COLORECTAL CANCER | AMAL THERAPEUTICS SA (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-3429618-B1 | COMBINATION OF AN IMMUNE CHECKPOINT MODULATOR AND A COMPLEX COMPRISING A CELL PENETRATING PEPTIDE, A CARGO AND A TLR PEPTIDE AGONIST FOR USE IN MEDICINE | AMAL THERAPEUTICS SA (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023213969-A1 | VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE | JUNO THERAPEUTICS GMBH (DE) | 2023-11-09 | — | — | WO | disclosed |
| EP-4195923-A1 | GREEN CLOSED LOOP BIO-WASTE REFINING PROCESS FOR PRODUCING SMART ACTIVE EXTRACTS AND DELIVERY SYSTEMS FOR THEIR APPLICATION | Cellacure LLC (US) | 2023-06-21 | — | — | EP | disclosed |
| US-20220305101-A1 | Fusion Comprising A Cell Penetrating Peptide, A Multi Epitope And A TLR Peptide Agonist For Treatment Of Cancer | AMAL THERAPEUTICS SA (CH) | 2022-09-29 | — | — | US | disclosed |
| US-20220175933-A1 | Novel Complex Comprising A Cell Penetrating Peptide, A Cargo And A TLR Peptide Agonist For Treatment Of Glioblastoma | AMAL THERAPEUTICS SA (CH) | 2022-06-09 | — | — | US | disclosed |
| US-11338027-B2 | Fusion comprising a cell penetrating peptide, a multi epitope and a TLR peptide agonist for treatment of cancer | AMAL THERAPEUTICS SA (CH) | 2022-05-24 | — | — | US | disclosed |
| US-20220118102-A1 | COMBINATION OF AN IMMUNE CHECKPOINT MODULATOR AND A COMPLEX COMPRISING A CELL PENETRATING PEPTIDE, A CARGO AND A TLR PEPTIDE AGONIST FOR USE IN MEDICINE | AMAL THERAPEUTICS SA (CH) | 2022-04-21 | — | — | US | disclosed |
| WO-2022036010-A1 | GREEN CLOSED LOOP BIO-WASTE REFINING PROCESS FOR PRODUCING SMART ACTIVE EXTRACTS AND DELIVERY SYSTEMS FOR THEIR APPLICATION | CELLACURE LLC (US) | 2022-02-17 | — | — | WO | disclosed |
| EP-3429618-A1 | COMBINATION OF AN IMMUNE CHECKPOINT MODULATOR AND A COMPLEX COMPRISING A CELL PENETRATING PEPTIDE, A CARGO AND A TLR PEPTIDE AGONIST FOR USE IN MEDICINE | Amal Therapeutics SA (CH) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017157964-A1 | COMBINATION OF AN IMMUNE CHECKPOINT MODULATOR AND A COMPLEX COMPRISING A CELL PENETRATING PEPTIDE, A CARGO AND A TLR PEPTIDE AGONIST FOR USE IN MEDICINE | AMAL THERAPEUTICS SA (CH) | 2017-09-21 | — | — | WO | disclosed |