SCHEMBL19358317

SCHEMBL19358317

O=Cc1ccc(OCCCC(=O)Nc2ccc(OCCCC(=O)O)cc2)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.58
GAA P10253 2/20 0.58
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50
PPARA Q07869 1/20 0.49
POLB P06746 3/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
PKM P14618 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
LTA4H P09960 1/20 0.46
CYP1A2 P05177 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19358295 0.93 GAA (0.50) L3MBTL1GAACNR1CNR2PPARA
SCHEMBL19358197 0.90 SMN1; SMN2 (0.54) L3MBTL1GAACNR1CNR2POLB
SCHEMBL19358277 0.88 TRIM24 (0.53) PPARAPOLBMAPT
SCHEMBL19358250 0.85 HPGD (0.46) CNR1CNR2MEN1KMT2ASMN1; SMN2
SCHEMBL2558549 0.84 ALB (0.57) PPARAPOLBMAPT
SCHEMBL19358303 0.84 SMN1; SMN2 (0.51) GAAMAPK1ALDH1A1MAPTSMN1; SMN2
SCHEMBL19358323 0.81 CNR1 (0.41) L3MBTL1CNR1CNR2POLBMAPK1
SCHEMBL19363269 0.80 ALDH1A1 (0.48) L3MBTL1POLBMAPK1ALDH1A1MAPT
SCHEMBL19358286 0.76 TYR (0.51) POLBMAPT
SCHEMBL19358288 0.76 TYR (0.51) L3MBTL1POLBMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149058-B2 Multi-functional chemical agents, and the method for protein modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2021-10-19 US disclosed
US-20210163526-A9 Multi-Functional Chemical Agents, and the Method for Protein Modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2021-06-03 US disclosed
US-20190085020-A1 Multi-Functional Chemical Agents, and the Method for Protein Modification DEPARTMENT OF BIOTECHNOLOGY (IN) 2019-03-21 US disclosed
EP-3442987-A1 MULTI-FUNCTIONAL CHEMICAL AGENTS, AND THE METHOD FOR PROTEIN MODIFICATION Department of Biotechnology (IN) 2019-02-20 EP disclosed
WO-2017158612-A1 MULTI-FUNCTIONAL CHEMICAL AGENTS, AND THE METHOD FOR PROTEIN MODIFICATION DEPARTMENT OF BIOTECHNOLOGY (IN) 2017-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149058-B2 Multi-functional chemical agents, and the method for protein modification FN1, LCP1, NPM1 L3MBTL1 597/4885GAA 3701/4885CNR1 4714/4885
US-20190085020-A1 Multi-Functional Chemical Agents, and the Method for Protein Modification FN1, LCP1, NPM1 L3MBTL1 597/4885GAA 3701/4885CNR1 4714/4885
US-20210163526-A9 Multi-Functional Chemical Agents, and the Method for Protein Modification FN1, LCP1, NPM1 L3MBTL1 597/4885GAA 3701/4885CNR1 4714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.