Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.70 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358846 | 0.89 | TP53 (0.67) | CXCR4OPRM1OPRK1CA2CA1 | |
| SCHEMBL4661775 | 0.87 | CA2 (0.76) | OPRM1OPRK1CA2CA1MAPT | |
| SCHEMBL19358860 | 0.86 | CXCR4 (0.82) | CXCR4OPRM1OPRK1CA2CA1 | |
| SCHEMBL30254760 | 0.86 | CXCR4 (0.78) | CXCR4OPRK1CA2CA1HTT | |
| SCHEMBL11615300 | 0.85 | RAB9A (0.74) | CA2MAPTSMN1; SMN2FFAR1NPC1 | |
| SCHEMBL6961817 | 0.85 | CA2 (0.68) | CA2SMN1; SMN2POLBFFAR1NPC1 | |
| SCHEMBL121841 | 0.83 | CYP19A1 (0.80) | OPRM1OPRK1CA2CA1MAPT | |
| SCHEMBL19358847 | 0.83 | CXCR4 (0.77) | CXCR4OPRM1OPRK1HTTMAPT | |
| SCHEMBL19358855 | 0.83 | CXCR4 (1.00) | CXCR4OPRM1OPRK1HTTMAPT | |
| SCHEMBL19358887 | 0.83 | MAPT (0.82) | CXCR4OPRM1OPRK1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429588-B1 | AMIDE-SULFAMIDE DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 INHIBITION | UNIV EMORY (US) | 2024-09-18 | — | — | EP | disclosed |
| US-10669270-B2 | Amide-sulfamide derivatives, compositions, and uses related to CXCR4 inhibition | EMORY UNIVERSITY (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190084980-A1 | Amide-Sulfamide Derivatives, Compositions, and Uses Related to CXCR4 Inhibition | EMORY UNIVERSITY (US) | 2019-03-21 | — | — | US | disclosed |
| EP-3429588-A1 | AMIDE-SULFAMIDE DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 INHIBITION | Emory University (US) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017160832-A1 | AMIDE-SULFAMIDE DERIVATIVES, COMPOSITIONS, AND USES RELATED TO CXCR4 INHIBITION | EMORY UNIVERSITY (US) | 2017-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084980-A1 | Amide-Sulfamide Derivatives, Compositions, and Uses Related to CXCR4 Inhibition | CXCR4, CXCL12, CXCR2 | CXCR4 1/4885OPRM1 190/4885OPRK1 112/4885 |
| US-10669270-B2 | Amide-sulfamide derivatives, compositions, and uses related to CXCR4 inhibition | CXCR4, CXCL12, CXCR2 | CXCR4 1/4885OPRM1 190/4885OPRK1 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.