Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360200 | 0.85 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL19360218 | 0.72 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL22944364 | 0.69 | DRD2 (0.39) | CHRNA7 | |
| SCHEMBL19360217 | 0.67 | CHRNA7 (0.30) | CHRNA7 | |
| SCHEMBL19360210 | 0.66 | — | — | |
| SCHEMBL19349846 | 0.64 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL22944092 | 0.63 | HDAC6 (0.59) | CHRNA7 | |
| SCHEMBL22944096 | 0.63 | HDAC6 (0.59) | CHRNA7 | |
| SCHEMBL19360207 | 0.62 | — | — | |
| SCHEMBL19362265 | 0.62 | CHRNA7 (0.35) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267679-A1 | TRICYCLIC FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF p97 COMPLEX | CLEAVE BIOSCIENCES INC (US) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267679-A1 | TRICYCLIC FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF p97 COMPLEX | PSMG3, PSME1, PSMB3 | CHRNA7 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.