Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944360 | 0.79 | DRD1 (0.48) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29795294 | 0.79 | DRD1 (0.48) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL22944089 | 0.78 | HDAC6 (0.58) | — | |
| SCHEMBL22944091 | 0.78 | HDAC6 (0.58) | — | |
| SCHEMBL22944367 | 0.77 | HDAC6 (0.41) | — | |
| SCHEMBL22944368 | 0.77 | HDAC6 (0.41) | — | |
| SCHEMBL22944361 | 0.77 | HDAC6 (0.41) | — | |
| SCHEMBL22944092 | 0.73 | HDAC6 (0.59) | CHRNA7 | |
| SCHEMBL22944096 | 0.73 | HDAC6 (0.59) | CHRNA7 | |
| SCHEMBL29795153 | 0.73 | DRD2 (0.61) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021979-A2 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |