Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.66 |
| ▸ | IDH1 | O75874 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360363 | 0.90 | RORC (0.65) | RORCIDH1PPARGACLY | |
| SCHEMBL19360299 | 0.89 | RORC (0.65) | RORCIDH1KIF11 | |
| SCHEMBL19360580 | 0.87 | RORC (0.63) | RORCKIF11 | |
| SCHEMBL19360374 | 0.84 | RORC (0.61) | RORCKIF11 | |
| SCHEMBL19360303 | 0.80 | RORC (0.64) | RORCPPARGKIF11 | |
| SCHEMBL19360366 | 0.80 | RORC (1.00) | RORC | |
| SCHEMBL19360300 | 0.79 | RORC (0.63) | RORCIDH1 | |
| SCHEMBL19360322 | 0.78 | RORC (0.49) | RORCIDH1KIF11 | |
| SCHEMBL19360548 | 0.78 | RORC (0.49) | RORCIDH1PPARGKIF11 | |
| SCHEMBL19360575 | 0.78 | RORC (0.65) | RORCKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |