Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360337 | 0.88 | RORC (0.75) | RORC | |
| SCHEMBL19360529 | 0.87 | RORC (0.59) | RORCHDAC6MLYCDMRGPRX1 | |
| SCHEMBL19360644 | 0.86 | RORC (0.54) | RORCHDAC6 | |
| SCHEMBL19360645 | 0.85 | RORC (0.54) | RORC | |
| SCHEMBL19360572 | 0.83 | RORC (0.48) | RORCHDAC6 | |
| SCHEMBL29016570 | 0.79 | RORC (0.83) | RORC | |
| SCHEMBL30370139 | 0.79 | RORC (0.83) | RORC | |
| SCHEMBL19360478 | 0.75 | RORC (0.69) | RORC | |
| SCHEMBL19360310 | 0.74 | RORC (0.77) | RORC | |
| SCHEMBL19360323 | 0.73 | RORC (0.76) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |