Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360645 | 0.88 | RORC (0.54) | RORCSMN1; SMN2 | |
| SCHEMBL19360572 | 0.88 | RORC (0.48) | RORCSMN1; SMN2HDAC6LMNA | |
| SCHEMBL19360338 | 0.86 | RORC (0.57) | RORCHDAC6 | |
| SCHEMBL19360477 | 0.86 | RORC (0.69) | RORC | |
| SCHEMBL19360481 | 0.78 | RORC (0.67) | RORC | |
| SCHEMBL29016570 | 0.77 | RORC (0.83) | RORC | |
| SCHEMBL30370139 | 0.77 | RORC (0.83) | RORC | |
| SCHEMBL28581339 | 0.75 | RORC (0.68) | RORC | |
| SCHEMBL19360638 | 0.75 | RORC (0.63) | RORCSMN1; SMN2 | |
| SCHEMBL19360452 | 0.75 | RORC (0.63) | RORCSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |