Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.65 |
| ▸ | GNRHR | P30968 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360300 | 0.90 | RORC (0.63) | RORCIDH1 | |
| SCHEMBL19360374 | 0.89 | RORC (0.61) | RORCKIF11 | |
| SCHEMBL19360367 | 0.89 | RORC (0.66) | RORCIDH1KIF11 | |
| SCHEMBL19360580 | 0.85 | RORC (0.63) | RORCKIF11 | |
| SCHEMBL19360363 | 0.78 | RORC (0.65) | RORCIDH1 | |
| SCHEMBL19360322 | 0.76 | RORC (0.49) | RORCIDH1KIF11 | |
| SCHEMBL19360371 | 0.76 | RORC (0.62) | RORCLMNA | |
| SCHEMBL19360575 | 0.76 | RORC (0.65) | RORCKIF11 | |
| SCHEMBL19360378 | 0.75 | RORC (0.64) | RORCIDH1 | |
| SCHEMBL22004147 | 0.73 | ACLY (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |