Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360397 | 0.89 | RORC (0.51) | RORC | |
| SCHEMBL18440701 | 0.84 | RORC (0.55) | RORC | |
| SCHEMBL19360394 | 0.83 | RORC (0.64) | RORC | |
| SCHEMBL19360604 | 0.79 | IDH1 (0.47) | RORCMRGPRX4 | |
| SCHEMBL20465147 | 0.79 | SRD5A2 (0.48) | RORC | |
| SCHEMBL18440704 | 0.78 | RORC (0.53) | RORC | |
| SCHEMBL19360521 | 0.76 | RORC (0.48) | RORC | |
| SCHEMBL19360594 | 0.74 | RORC (0.42) | RORC | |
| SCHEMBL20465183 | 0.73 | RORC (0.42) | RORC | |
| SCHEMBL19360388 | 0.72 | RORC (0.55) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |