Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360401 | 0.89 | RORC (0.51) | RORC | |
| SCHEMBL19360388 | 0.85 | RORC (0.55) | RORCKDM4EACSS2CNR2 | |
| SCHEMBL19360394 | 0.82 | RORC (0.64) | RORC | |
| SCHEMBL19360605 | 0.82 | IDH1 (0.47) | RORCKDM4ENR1H4ACSS2CNR2 | |
| SCHEMBL19360520 | 0.78 | KIF11 (0.51) | RORCKDM4EACSS2 | |
| SCHEMBL18440914 | 0.76 | RORC (0.52) | RORCKDM4E | |
| SCHEMBL19360593 | 0.75 | KDM4E (0.43) | RORCKDM4EACSS2 | |
| SCHEMBL20634743 | 0.75 | RORC (0.46) | RORCKDM4ECNR2 | |
| SCHEMBL19360398 | 0.75 | HTT (0.45) | RORCKDM4ENR1H4 | |
| SCHEMBL18440701 | 0.73 | RORC (0.55) | RORCACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |